Perineural invasion means that cancer cells were seen surrounding or tracking along a nerve fiber within the prostate. When this is found on a biopsy, it means that there is a higher chance that the cancer has spread outside the prostate.
Similarly one may ask, how is perineural invasion treated?
Perineural invasion (PNI) is an uncommon manifestation of cutaneous squamous cell carcinoma (SCC). Patients with perineural invasion carry a much higher risk for local and distant recurrence and may require more aggressive treatment including Mohs micrographic surgery and adjuvant radiation.
Also, is perineural invasion dangerous?
"Perineural invasion" on biopsy means that there is an increased chance that cancer could spread out of the prostate, but Gleason grade and amount of cancer in the cores are more important. Even with perineural invasion your cancer could still be very curable depending on other factors.
Is perineural invasion metastasis?
Perineural invasion (PNI) can be found in a variety of malignant tumors. It is a sign of tumor metastasis and invasion and portends the poor prognosis of patients.
What is perineural infusion?
Perineural local anesthetics are administered by continuous infusion with or without patient-controlled analgesia (PCA). Inpatient perineural local anesthetic infusion can be administered by mechanical infusion pump, such as the kind used for IV PCA and epidural analgesia.