What causes Cin?

The main cause of CIN is the human papilloma virus (HPV). There are over 100 types of HPV. Some types can affect the cervix and cause the abnormal cell changes that may develop into cervical cancer. These types of HPV are called high-risk HPV.

Then, what is the difference between CIN 1 and CIN 2?

Low-grade neoplasia (CIN 1) refers to dysplasia that involves about one-third of the thickness of the epithelium. CIN 2 refers to abnormal changes in about one-third to two-thirds of the epithelial layer. CIN 3 (the most severe form) describes a condition that affects more than two-thirds of the epithelium.

Beside above, how long does it take CIN 1 to go away?

CIN-1 is due to infection with HPV (human papilloma virus). Of every 10 cases of HPV infection, eight will go away without treatment within 12 months. In addition to CIN changes, other minor abnormalities are commonly seen. These often need follow-up but do not necessarily mean that precancerous changes are developing.

Is Cin curable?

Most of the time, cases of CIN can be treated successfully. Ablation and resection are effective in about 90% of all cases, with a 10% chance of recurrence of CIN after treatment. It only rarely progresses to cancer, and when it does progress, it does so very slowly.

Is CIN 1 common?

Introduction. Cervical intraepithelial neoplasia grade 1 (CIN1) is the most common histologic biopsy diagnosis following referral for colposcopy for a positive cervical cancer-screening test.

Does cin1 mean I have HPV?

CIN 1 is usually caused by certain types of human papillomavirus (HPV) and is found when a cervical biopsy is done. CIN 1 is not cancer and usually goes away on its own without treatment. CIN 1 is sometimes called low-grade or mild dysplasia. Also called cervical squamous intraepithelial neoplasia 1.

Does HPV stay with you for life?

Does HPV go away? Depending on the type of HPV that you have, the virus can linger in your body for years. In most cases, your body can produce antibodies against the virus and clear the virus within one to two years. Most strains of HPV go away permanently without treatment.

What is cin1 cin2 cin3?

The cell changes can be classed as CIN1, 2 or 3. Treatment is usually given to remove CIN2 or CIN3 abnormal cells, also called moderate or severe dyskaryosis or dysplasia (see 'Treatments and their impacts'). CIN1 – indicates mild changes; affecting only one-third of the thickness of the surface layer of the cervix.

Can you have CIN without HPV?

HPV infection is necessary but not sufficient to develop CIN. More than 90% of infections are spontaneously cleared by the immune system within one year without treatment. Approximately 60% of CIN 1 lesions regress without treatment and less than 1% progress to cancer.

Is Cin contagious?

Cervical cancer only affects women/girls. It is not contagious and cannot be passed on to other people. These abnormal cells are not cancerous, and are called cervical intra-epithelial neoplasia (CIN). CIN may also be referred to as dysplasia or dyskaryosis.

What does CIN 3 mean?

CIN 3. Listen to pronunciation. Severely abnormal cells are found on the surface of the cervix. CIN 3 is usually caused by certain types of human papillomavirus (HPV) and is found when a cervical biopsy is done. CIN 3 is not cancer, but may become cancer and spread to nearby normal tissue if not treated.

Can CIN come back?

Patients can return to annual screening once they ahve both a negative cervical cytology and HPV test, or two consecutive negative tests. Women diagnosed with CIN 2 or 3 require annual surveillance for 20 years.

What does Cin mean?

Cervical intraepithelial neoplasia

Is cin2 precancerous?

Abnormal squamous cells

HSIL, previously graded as CIN 2 or CIN 3, are precancerous. This means that although they do not usually cause symptoms, high-grade abnormalities have the potential to develop into early cervical cancer over about 10–15 years if they are not detected and treated.

Is HPV a STD?

HPV is the most common sexually transmitted infection (STI). HPV is a different virus than HIV and HSV (herpes). 79 million Americans, most in their late teens and early 20s, are infected with HPV. There are many different types of HPV.

How is CIN diagnosed?

Since CIN usually does not cause any symptoms, a Pap smear is needed to find abnormal cells. The doctor will look through colored lenses to see whether there are any abnormal cells on the cervix or vaginal walls. A biopsy may be performed to remove tissue samples for examination in a laboratory.

What is CIN 3 of the cervix?

CIN 3. Severely abnormal cells are found on the surface of the cervix. CIN 3 is usually caused by certain types of human papillomavirus (HPV) and is found when a cervical biopsy is done. CIN 3 is not cancer, but may become cancer and spread to nearby normal tissue if not treated.

How long can HPV dormant?

How long can HPV lay dormant? HPV can lay dormant for many years after a person contracts the virus, even if symptoms never occur. Most cases of HPV clear within 1 to 2 years as the immune system fights off and eliminates the virus from the body.

What does it mean if I have CIN 1?

CIN 1. Slightly abnormal cells are found on the surface of the cervix. CIN 1 is usually caused by certain types of human papillomavirus (HPV) and is found when a cervical biopsy is done. CIN 1 is not cancer and usually goes away on its own without treatment.