The osteoclasts remove bone by dissolving the mineral and breaking down the matrix in a process that is called bone resorption. The osteoclasts come from the same precursor cells in the bone marrow that produce white blood cells.
Then, what cell is involved in bone resorption?
Additionally, what is bone deposition and resorption?
The osteoblasts secrete an organic matrix composed largely of collagen protein, which becomes hardened by deposits of hydroxyapatite. This process is called bone deposition. Bone resorption (dissolution of hydroxyapatite), produced by the action of osteoclasts (fig.
Why are osteoclasts important in bone growth?
Osteoclasts are the cells that degrade bone to initiate normal bone remodeling and mediate bone loss in pathologic conditions by increasing their resorptive activity. Recent studies have identified functions for OCPs and osteoclasts in and around bone other than bone resorption.
How does bone Remodelling occur?
Bone remodeling (or bone metabolism) is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation). In the first year of life, almost 100% of the skeleton is replaced.